Emergency services were called to the scene at the New County Hotel, Perth, at around 5.02am on Monday.
On Monday morning, a fire broke out at a hotel in Perth, killing three people and a dog.
On December 2, at around 5.02 am, emergency personnel were called to the scene at the New County Hotel in County Place.
The Scottish Incident and Rescue Service (SFRS) confirmed to STV News that the fire claimed the lives of at least three humans and a dog.
The Scottish Ambulance Services treated a number of individuals for minor wounds.
Crews are still on the scene after the fire has been put out to conduct safety checks.
Police Scotland confirmed a “number of guests” had been evacuated from the building, alongside two people from a neighbouring block of flats.
Chief superintendent Phil Davison said: “Our thoughts are very much with the families and loved ones of those who have died at what is a very difficult time for everyone.
“Our enquiries are ongoing to establish the full circumstances of what has happened and officers are conducting a joint investigation with the Scottish Fire and Rescue Service.”
Deputy First Minister John Swinney described the fatalities as “heart breaking news”.
Mr Swinney, the MSP for Perthshire North, tweeted: “My sympathies with all affected by this tragedy.”
Deputy leader of Perth & Kinross Council, councillor Eric Drysdale, warned members of the public that it was a “very serious incident”.
He added: “All announcements regarding any confirmed casualties will be made by the emergency services.
“Roads around the scene, specifically County Place, Leonard Street, New Row and Hospital Street, are closed. Please avoid the area today.”
A spokesperson for the Scottish Fire and Rescue Service said: “We are currently in attendance alongside emergency service partners at a commercial building fire at County Place in Perth.
“Operations Control mobilised nine fire appliances to the scene after the alarm was raised at 5.02am on Monday, January 2.”
A Scottish Ambulance Service spokesperson “We received a call from Scottish Fire and Rescue Service of a fire at the New County Hotel in Fife at 5.05am.
“We responded with 21 resources including our Special Operation Resource Team, with our first resource on scene at 5.12am.”